Insulin Resistance and Transplantation

Deborah Wyatt wrote:

> Dr. Lundin,

> I am greatly concerned about the possiblity of becoming diabetic if I get

> a transplant. Especially since hearing about insulin resistent diabetes.

> My father is diabetic, and my maternal grandfather was diabetic. I see

> no point in getting a transplant if it is going to result in yet another

> chronic disease. Can you elaborate on this 'insulin resistant diabetes'?

> How do you ever get it under control?

> Debbie Wyatt

> Bothell, WA

> ladyrain@seanet.com

Insulin resistance means that you body's cells that need insulin need more than normal thus they are considered resistant to insulin. I doesn't mean that they won't respond to higher levels of insulin. There are newer medications that make the cells more sensitive to insulin. Much is happening in the treatment of diabetes and prevention of problems. With your family history the risk of getting diabetes post-transplant is not inconsequential. You will have to decide how important it is to you to have the transplant. The diabetes can be managed today with fewer side effects and complications than your ancestors experienced. It all depends on whether or not you want to risk the experience.

Peter Lundin, M.D.

June 11, 1998

from DIALYSIS ONLINE

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